What is this test?
The test measures very low concentrations of total IgE with a highly sensitive method. It does not indicate which specific allergen the antibodies are targeting.
Why might it be ordered?
- In a specialized evaluation when very low values of total IgE are expected.
- As supplementary information for the interpretation of low specific IgE results.
What sample is needed?
A healthcare professional collects a venous blood sample. Depending on the method, the laboratory uses serum or plasma.
How should you prepare?
Tell the laboratory about all medicines, hormone treatments, vitamins and supplements you take. Do not stop or change treatment unless your clinician tells you to. Follow any instructions about fasting and the time of collection.
How should you understand the result?
A low or detectable value alone does not confirm or exclude an allergy; clinical history and specific IgE are more important for a particular allergen. Your result is interpreted using the reference interval on the laboratory report and in the context of your symptoms, medical history and other test findings.
Sources and editorial status
This patient-facing text is an editorial draft. It should be approved by a laboratory physician before official publication.