What is this test?
Total IgE measures the total amount of immunoglobulin E in the blood. This type of antibody is involved in allergic reactions and in the defense against certain parasites.
Why might it be ordered?
- As supplementary information in the evaluation of atopic or allergic disease.
- In certain immune, skin or parasitic conditions and before certain biologic therapies.
What sample is needed?
A healthcare professional collects a venous blood sample. Depending on the method, the laboratory uses serum or plasma.
How should you prepare?
Tell the laboratory about all medicines, hormone treatments, vitamins and supplements you take. Do not stop or change treatment unless your clinician tells you to. Follow any instructions about fasting and the time of collection.
How should you understand the result?
Elevated total IgE does not indicate what the reaction is to and may be present in eczema, parasites and other conditions. A normal total IgE does not rule out a specific allergy. Your result is interpreted using the reference interval on the laboratory report and in the context of your symptoms, medical history and other test findings.
Sources and editorial status
This patient-facing text is an editorial draft. It should be approved by a laboratory physician before official publication.